Published January 1, 2022 | Version v1
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An acetonic extract and secondary metabolites from the endolichenic fungus Nemania sp. EL006872 exhibit immune checkpoint inhibitory activity in lung cancer cell

  • 1. Sunchon Natl Univ, Coll Pharm, Sunchon, South Korea
  • 2. Sookmyung Womens Univ, Coll Pharm, Seoul, South Korea
  • 3. Marmara Univ, Fac Arts & Sci, Dept Biol, Istanbul, Turkey
  • 4. Sunchon Natl Univ, Korean Lichen Res Inst, Sunchon, South Korea

Description

Background: Endolichenic fungi (ELF), which live the inside the lichen thallus, contain many secondary metabolites that show various biological activities. Recent studies show that lichen and ELF secondary metabolites have antioxidant, antibacterial, antifungal, cytotoxic, and anticancer activities.

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