Evaluation of the antiulcerogenic activity profile of a flavonol diglucoside from Equisetum palustre L.

Ethnopharmacological relevance: The aerial parts of Equisetum palustre L are used to treat peptic ulcer disease in Turkey. In a previous study, a flavonol diglucoside i.e., kaempferol 3-O-1 ''-beta-D-n-glucopyranosyl-3-O-1 '''-beta-D-glucopyranoside (KGG) was isolated as the major antiulcerogenic constituent from the plant. Aim of the study: The present study was undertaken to evaluate the antiulcer activity profile of KGG using various in vivo experimental ulcer models as well as by assessing gastric biochemical parameters.