Cross sections for the reactions ${e}^{+}{e}^{-}\to {K}^{+}{K}^{-}{\pi }^{+}{\pi }^{-}\left({\pi }^{0}\right)$, ${K}^{+}{K}^{-}{K}^{+}{K}^{-}\left({\pi }^{0}\right)$, ${\pi }^{+}{\pi }^{-}{\pi }^{+}{\pi }^{-}\left({\pi }^{0}\right)$, $p\overline{p}{\pi }^{+}{\pi }^{-}\left({\pi }^{0}\right)$ in the energy region between 3.773 and 4.600 GeV

Using the data samples collected in the energy range from 3.773 to 4.600 GeV with the BESIII detector at the BEPCII collider, we measure the dressed cross sections as a function of center-of-mass energy for ${e}^{+}{e}^{-}\to {K}^{+}{K}^{-}{\pi }^{+}{\pi }^{-}\left({\pi }^{0}\right)$, ${K}^{+}{K}^{-}{K}^{+}{K}^{-}\left({\pi }^{0}\right)$, ${\pi }^{+}{\pi }^{-}{\pi }^{+}{\pi }^{-}\left({\pi }^{0}\right)$, and $p\overline{p}{\pi }^{+}{\pi }^{-}\left({\pi }^{0}\right)$. The cross sections for ${e}^{+}{e}^{-}\to {K}^{+}{K}^{-}{K}^{+}{K}^{-}{\pi }^{0}$, $p\overline{p}{\pi }^{+}{\pi }^{-}\left({\pi }^{0}\right)$ are the first measurements. Cross sections for the other five channels are much more precise than previous results in this energy region. We also search for charmonium and charmonium-like resonances, such as the $Y\left(4230\right)$, decaying into the same final states. We find evidence of the $\psi \left(4040\right)$ decaying to ${\pi }^{+}{\pi }^{-}{\pi }^{+}{\pi }^{-}{\pi }^{0}$ with a statistical significance of $3.6\sigma $. Upper limits are provided for other decays since no clear signals are observed.