Published January 1, 2022
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Comparative evaluation of relaxant effects of three prangos species on mouse corpus cavernosum: Chemical characterization and the relaxant mechanisms of action of P. pabularia and (+)-oxypeucedanin
Creators
- 1. Ege Univ, Fac Pharm, Dept Pharmacol, Izmir, Turkey
- 2. Ege Univ, Fac Pharm, Dept Pharmaceut Bot, TR-35040 Izmir, Turkey
Description
Ethnopharmacological relevance: Erectile dysfunction (ED) is the most common form of sexual dysfunction which has been the topic of great interest through the history by all cultures. It is now among the most treated health problems in men of all ages that develop under the influence of lifestyle factors and some diseases. Plants are extensively used to cure sexual dysfunction for centuries. Roots of Prangos sp. have been used to improve sexual performance in Anatolian traditional medicine and are rich of coumarin, furanocoumarin and their derivatives. Scientific research is necessary to support and validate the ethno-traditional uses of these plants.
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