Published January 1, 2021
| Version v1
Journal article
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CD4+and CD25+T-cell response to short-time interferon-beta therapy on IL10, IL23A and FOXP3 genes in multiple sclerosis patients
Creators
- 1. Yeditepe Univ, Dept Med Biol, Fac Med, TR-34755 Istanbul, Turkey
- 2. Univ Hlth Sci, Erenkoy Mental & Nervous Dis Training & Res Hosp, Dept Neurol, Istanbul, Turkey
- 3. Acibadem Mehmet Ali Aydinlar Univ, Dept Histol & Embryol, Fac Med, Istanbul, Turkey
Description
Aim of the Study Interferon-beta (IFN-beta), multiple sclerosis (MS) drug for years, does not have therapeutic effects on each patient. Yet, a considerable portion has experienced no therapeutic response to IFN-beta. Therefore, it is necessary to determine disease-specific biomarkers that affect drug response. Here, we aimed to determine the effects of interleukin 10 (IL10) and 23 (IL23A), as well as forkhead box P3 (FOXP3) genes on MS after IFN-beta therapy.
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