Yayınlanmış 1 Ocak 2010 | Sürüm v1
Dergi makalesi Açık

Expression of Angiogenic Factors in Craniopharyngiomas: Implications for Tumor Recurrence

  • 1. Marmara Univ, Inst Neurol Sci, Mol Neurosurg Lab, TR-34853 Istanbul, Turkey
  • 2. Marmara Univ, Inst Neurol Sci, Pathol Lab, TR-34853 Istanbul, Turkey
  • 3. Marmara Univ, Fac Med, Dept Pathol, TR-34853 Istanbul, Turkey
  • 4. Marmara Univ, Dept Neurosurg, Fac Med, TR-34853 Istanbul, Turkey

Açıklama

BACKGROUND: The primary treatment for craniopharyngiomas is total excision, but recurrence is common. However, current knowledge on the mechanisms of recurrence is limited. OBJECTIVE: We hypothesized that recurrence is linked to the angiogenesis of the tumor. Recurrent and nonrecurrent tumor samples were compared with regard to expression of angiogenesis-related factors and angiogenic capacity in a corneal angiogenesis model.

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