Published January 1, 2010
| Version v1
Journal article
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Expression of Angiogenic Factors in Craniopharyngiomas: Implications for Tumor Recurrence
Creators
- 1. Marmara Univ, Inst Neurol Sci, Mol Neurosurg Lab, TR-34853 Istanbul, Turkey
- 2. Marmara Univ, Inst Neurol Sci, Pathol Lab, TR-34853 Istanbul, Turkey
- 3. Marmara Univ, Fac Med, Dept Pathol, TR-34853 Istanbul, Turkey
- 4. Marmara Univ, Dept Neurosurg, Fac Med, TR-34853 Istanbul, Turkey
Description
BACKGROUND: The primary treatment for craniopharyngiomas is total excision, but recurrence is common. However, current knowledge on the mechanisms of recurrence is limited. OBJECTIVE: We hypothesized that recurrence is linked to the angiogenesis of the tumor. Recurrent and nonrecurrent tumor samples were compared with regard to expression of angiogenesis-related factors and angiogenic capacity in a corneal angiogenesis model.
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