Published January 1, 2021
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Changes in choline and cholinesterase in saliva of dogs with parvovirus infection
Creators
- 1. Bursa Uludag Univ, Fac Vet Med, Dept Internal Med, TR-16059 Bursa, Turkey
- 2. Univ Murcia, Interlab UMU, Interdisciplinary Lab Clin Anal, Reg Campus Int Excellence,Campus Mare Nostrum, E-30100 Murcia, Spain
- 3. Bursa Uludag Univ, Fac Med, Dept Pharmacol, TR-16059 Bursa, Turkey
Description
This study investigated the changes in choline (Ch) and butyrylcholinesterase (BChE) in saliva in canine parvovirosis (CP) as a model of sepsis, and their correlations with these analytes in serum and with other markers of inflammation such as white blood cell count (WBC) and serum C-reactive protein (CRP). A total of 30 dogs with CP were sampled for saliva and serum at presentation, and 10 healthy puppies were also sampled as controls. Salivary Ch was higher in dogs with CP (P < 0.001) showing a positive correlation with CRP, whereas no differences were observed in salivary BChE. This is the first report in which Ch is measured in saliva of dogs and based in the results of this study, salivary Ch could be potentially used as biomarker of the severity of CP.
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