Published January 1, 2022
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ALX-Related Frontonasal Dysplasias: Clinical Characteristics and Surgical Management
- 1. Hacettepe Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, TR-06080 Ankara, Turkey
- 2. Anadolu Med Ctr, Dept Plast & Reconstruct Surg, Istanbul, Turkey
- 3. Suleyman Demirel Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, Isparta, Turkey
Description
Aim: The term frontonasal dysplasia (FND) represents a spectrum of anomalies and its genetics have not been well defined. Recently, the critical role of the aristaless-like homeobox (ALX) gene family on the craniofacial development has been discovered. In the present study, we aimed to propose a systematic surgical treatment plan for the ALX-related FNDs according to the genotypic classification as well as demonstrating their clinical characteristics to help surgeons diagnose the underlying pathology accurately.
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