Published January 1, 2021
| Version v1
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Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications
Creators
- 1. Istinye Univ, Inst Hlth Sci, Dept Stem Cell & Tissue Engn, Istanbul, Turkey
- 2. Tecnol Monterrey, Dept Bioengn, Campus Monterrey, Monterrey 64849, Nuevo Leon, Mexico
Description
Layered double hydroxides (LDHs), when incorporated into biomaterials, provide a tunable composition, controllable particle size, anion exchange capacity, pH-sensitive solubility, high-drug loading efficiency, efficient gene and drug delivery, controlled release and effective intracellular uptake, natural biodegradability in an acidic medium, and negligible toxicity. In this review, we study potential applications of LDH-based nanocomposite scaffolds for tissue engineering. We address how LDHs provide new solutions for nanostructure stability and enhance in vivo studies' success.
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