Yayınlanmış 1 Ocak 2021
| Sürüm v1
Dergi makalesi
Açık
The Impact of Shift Type on Oxidative Stress, Inflammation, and Platelet Activation
Oluşturanlar
- 1. Hipokrat Labs, Dept Biochem, TR-34725 Istanbul, Turkey
- 2. Community Hlth Ctr, Karaman, Turkey
Açıklama
Objective: Rotating shift is known to disrupt circadian rhythms. The 12/24 shift system, with frequent day-night rotations and the ergonomic shift system (ESS), with 90% less rotations were compared for their impacts on oxidative stress, inflammation, and platelet activation by using pentraxin 3 (PTX3), urinary 15-isoprostane F2t, and 11-dehydrotromboxane B-2 (11-DTB2). Methods: All tests were performed by enzyme linked immunosorbent assay (ELISA). Unpaired t test and Pearson correlation analysis were employed. Results: Two hundred twenty 12/24 and 198 ESS workers were included. Plasma PTX3 and urinary 15-isoprostane F2t levels were not different between groups. Urinary 11-DTB2 in 12/24 workers were found significantly higher compared with ESS workers (P < 0.0001). A weak but significant correlation was found between urinary 15-isoprostane F2t and urinary 11-DTB2 levels (r = 0.17, P = 0.001). Conclusions: 12/24 rotating shift was found to cause platelet activation disturbances.
Dosyalar
bib-a17a94fe-678c-48b7-a7b0-663eff1f08c5.txt
Dosyalar
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