Published January 1, 2021
| Version v1
Journal article
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Proteomic Analysis of a hom-Disrupted, Cephamycin C Overproducing Streptomyces clavuligerus
Creators
- 1. Ondokuz Mayis Univ, Dept Agr Biotechnol, TR-55139 Samsun, Turkey
- 2. Erciyes Univ, Dept Biol, TR-38280 Kayseri, Turkey
- 3. Ernst Moritz Arndt Univ Greifswald, Inst Microbiol, D-17487 Greifswald, Germany
- 4. Middle East Tech Univ, Dept Biol Sci, TR-06800 Ankara, Turkey
Description
Background: Streptomyces clavuligerus is prolific producer of cephamycin C, a medically important antibiotic. In our former study, cephamycin C titer was 2-fold improved by disrupting homoserine dehydrogenase (hom) gene of aspartate pahway in Streptomyces clavuligerus NR-RL 3585.
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