Yayınlanmış 1 Ocak 2021 | Sürüm v1
Dergi makalesi Açık

Targeting oncogenic WIP1 phosphatase sensitizes hypoxic breast cancer cells to doxorubicin induced apoptosis via activation of p53-p21 axis

  • 1. Univ Aydin Adnan Menderes, Fac Med, Dept Med Biol, Aytepe Campus, Aydin, Turkey

Açıklama

Background: Oncogenic PPM1D/Wip1 phosphatase is negative regulator of chemotherapy responses. Hypoxia is a common feature of solid tumors associated with poor prognosis and resistance to radiotherapy and chemotherapy.

Dosyalar

bib-e30238b2-29d0-4b44-b337-f288088d716b.txt

Dosyalar (203 Bytes)

Ad Boyut Hepisini indir
md5:e865a7fdd92004a2c7f51bf86ae49bf6
203 Bytes Ön İzleme İndir