Yayınlanmış 1 Ocak 2021
| Sürüm v1
Dergi makalesi
Açık
A novel nano-hydroxyapatite/synthetic polymer/bone morphogenetic protein-2 composite for efficient bone regeneration
Oluşturanlar
- 1. Osaka Univ, Grad Sch Med, Orthopaed Surg, 2-2 Yamadaoka, Suita, Osaka 5650871, Japan
- 2. Hacettepe Univ, Med Fac, Dept Sports Med, Ankara, Turkey
- 3. Natl Hosp Org Osaka Natl Hosp, Dept Orthopaed Surg, Osaka, Japan
- 4. Minoh City Hosp, Dept Orthopaed Surg, Osaka, Japan
- 5. Univ Tokyo, Grad Sch Med Bone & Cartilage Regenerat Med, Tokyo, Japan
- 6. Hacettepe Univ, Grad Sch Sci & Engn, Dept Bioengn, Ankara, Turkey
- 7. Hacettepe Univ, Grad Sch Hlth Sci, Dept Stem Cell Sci, Ankara, Turkey
- 8. Hacettepe Univ, Med Fac, Dept Histol & Embryol, Ankara, Turkey
- 9. Toyonaka City Hosp, Dept Orthopaed Surg, Osaka, Japan
Açıklama
BACKGROUND: Efficient bone regeneration using recombinant human bone morphogenetic protein-2 (BMP-2) is needed to reduce side effects caused by high-dose BMP-2 use. The composite material of polylactic acid-polyethene glycol (PLA-PEG) for sustained release and an osteogenic nano-hydroxyapatite (nHAp) can contribute to efficient bone regeneration by BMP-2.
Dosyalar
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Dosyalar
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