BIOACTIVITY AND ANTIMICROBIAL PROPERTIES OF PMMA/Ag2O ACRYLIC BONE CEMENT COLLAGEN COATED

PMMA/Ag2O bone cements with collagen coating were prepared in order to improve their biomineralisation, biocompatibitity and antibacterial properties as well. ATR FTIR spectroscopy analysis demonstrated that collagen electrodeposition on their surface depends on the silver content in samples. In vitro tests, performed in simulated body fluid (SBF) during three weeks of SBF incubation, revealed the dissolution profile of Ag+ from the acrylic matrix, the results being in concordance with antibacterial tests performed against Escherichia coli and Staphylococcus aureus. The mineralization process upon incubation was confirmed by the surface morphology analyses (SEM) combined with ATR FTIR, which evidenced the phosphate characteristic bands of hydroxyapatite, depending on the silver oxide content in the samples.