Published January 1, 2011
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N-acylbenzotriazole mediated microwave assisted synthesis of protected and novel unprotected ferrocenoylamidoamino acids
- 1. Anadolu Univ, Fac Sci, Dept Chem, TR-26470 Eskisehir, Turkey
- 2. Eskisehir Osmangazi Univ, Fac Sci & Art, Dept Chem, Eskisehir, Turkey
Description
In this study, crystalline and chirally stable carboxyl-protected and novel unprotected N-ferrocenoyl amino acid derivatives of Ser, Cys, Ala, Phe, Trp, Asp and Asn have been prepared. These amino acids undergo substitution reaction with 1-(ferrocenylcarbonyl)-1H-benzotriazole, 1, in partially aqueous media under microwave irradiation. (C) 2011 Elsevier B.V. All rights reserved.
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