Published January 1, 2011
| Version v1
Journal article
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Drug resistant MCF-7 cells exhibit epithelial-mesenchymal transition gene expression pattern
Creators
- 1. Middle E Tech Univ, Dept Biol Sci, TR-06531 Ankara, Turkey
- 2. Gulhane Mil Med Acad, Dept Oncol, TR-06018 Ankara, Turkey
- 3. Ankara Oncol Hosp, Dept Gen Surg, TR-06460 Ankara, Turkey
- 4. Ankara Oncol Hosp, Dept Pathol, TR-06460 Ankara, Turkey
Description
Purpose: Multidrug resistance is resistance to structurally unrelated anticancer agents. Large-scale expression analysis by using high-density oligonucleotide microarrays may provide information about new candidate genes contributing to MDR. This study demonstrates alterations in expression levels of several genes related to epithelial-mesenchymal transition (EMT) in paclitaxel, docetaxel, and doxorubicin resistant MCF-7 cells.
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