Published January 1, 2011 | Version v1
Journal article Open

In-situ gel formulations of econazole nitrate: preparation and in-vitro and in-vivo evaluation

  • 1. Ege Univ, Fac Pharm, Dept Pharmaceut Technol, TR-35100 Izmir, Turkey
  • 2. Ege Univ, Fac Med, Dept Microbiol & Clin Microbiol, TR-35100 Izmir, Turkey
  • 3. Ege Univ, Fac Med, Dept Pathol, TR-35100 Izmir, Turkey
  • 4. Queens Univ Belfast, Ctr Med Biol, Sch Pharm, Belfast BT9 7BL, Antrim, North Ireland

Description

Objectives This study describes the in-situ gelling of econazole nitrate containing thermosensitive polymers composed of poloxamer 407 and 188 as a novel treatment platform for vaginal candidiasis.

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