Assessment of seasonal and sex-related variability of biomarkers in carp (Cyprinus carpio L.) from Karakaya Dam Lake, Turkey

This study examines seasonal changes in the activities of selected biomarkers in carp (Cyprinus carpi L.) from Karakaya Dam Lake and evaluates the influence of gender and environmental factors on those activities. Physicochemical characteristics of water were evaluated in the lakewater. Fish were sampled on seasonal basis, and liver ethoxyresorufin-O-deethylase (EROD), glutathione-S-transferase, glutathione reductase, plasma lactate dehydrogenase, aspartate and alanine aminotransferase, and brain acetylcholinesterase (AChE) activities were assayed. Plasma vitellogenin level and hepatosomatic index and condition factors were also determined. Strong seasonal variations were observed but there were no gender differences among selected markers. The highest vitellogenin level of male fish was detected as 606 ng/mL which represents the estrogenicity of water in the lake in September 2005. In addition, the seasonal changes of some biomarkers such as EROD and AChE showed that the lake may be at risk of pollution by some xenobiotics arising from agricultural and/or industrial activities. (C) 2011 Elsevier B.V. All rights reserved.