Published January 1, 2011 | Version v1
Journal article Open

Toll-like receptor expression in monocytes in patients with chronic kidney disease and haemodialysis: relation with inflammation

  • 1. Marmara Univ, Sch Med, Div Nephrol, Dept Internal Med, Istanbul, Turkey
  • 2. Tulane Univ, Sch Med, Dept Cardiol, New Orleans, LA 70112 USA
  • 3. Marmara Univ, Sch Med, Dept Infect Dis, Istanbul, Turkey
  • 4. Marmara Univ, Sch Med, Dept Internal Med, Div Immunol, Istanbul, Turkey
  • 5. Univ Ghent, Dept Internal Med, Div Nephrol, B-9000 Ghent, Belgium

Description

Background. Inflammation is one of the main contributors to atherosclerosis in haemodialysis (HD) patients. Activation of Toll-like receptors (TLRs) leads to inflammatory response. In this study, we aimed to evaluate the expression of TLRs on monocytes and relate their expression with inflammation in chronic kidney disease (CKD) and HD patients.

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