Published January 1, 2013 | Version v1
Journal article Open

Synthesis of novel 1,4-naphthoquinone derivatives: antibacterial and antifungal agents

  • 1. Istanbul Univ, Fac Engn, Dept Chem, Istanbul, Turkey
  • 2. Beykent Univ, Fac Engn & Architecture, Dept Chem Engn, Istanbul, Turkey
  • 3. Natl Univ Lviv Polytech, Dept Technol Biol Act Subst Pharm & Biotechnol, Lvov, Ukraine

Description

A novel series of substituted 1,4-naphthoquinone derivatives was synthesized and evaluated for antibacterial and antifungal activity. The structures of the novel products were characterized by spectroscopic methods. Among the tested compounds, 3a and 9 are the most effective compounds against M. luteum as potent antibacterial and C. tenuis and A. niger as potent antifungal. These two compounds are promising as biologically active compounds.

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