Published January 1, 2013 | Version v1
Journal article Open

Monoglycoconjugated phthalocyanines: Effect of sugar and linkage on photodynamic activity

  • 1. Univ Lyon 1, CNRS, Lab Chim Organ Glycochim ICBMS UMR 5246 2, F-69622 Villeurbanne, France
  • 2. Gebze Inst Technol, Dept Chem, TR-41400 Gebze, Kocaeli, Turkey
  • 3. Univ Hull, Dept Chem, Kingston Upon Hull HU6 7RX, East Yorkshire, England
  • 4. Univ Lyon 1, CNRS, Ctr Commun Spectrometrie Masse UMR 5246, F-69622 Villeurbanne, France

Description

Background: Click chemistry can be advantageously used to graft carbohydrates on phthalocyanines which are potent photosensitisers, but the effect of the presence of triazole moieties on photodynamic efficiency was not investigated systematically to date. The nature and linkage of the sugar were investigated in order to define structure activity relationships.

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