Published January 1, 2013
| Version v1
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Zantholic acid, a new monoterpenoid from Zanthoxylum zanthoxyloides
Creators
- 1. CSIR Cent Inst Med & Aromat Plants, Lucknow 226015, Uttar Pradesh, India
- 2. Babasaheb Bhimrao Ambedkar Univ, Lucknow 226025, Uttar Pradesh, India
- 3. Univ Douala, Inst Fisheries Sci, Douala 24157, Cameroon
Description
From the extract of Zanthoxylum zanthoxyloides fruits, a new menthane monoterpenoid, (4R,7R)-8-carboxy-7,9-dihydroxy-trans-menthane, tentatively, named as zantholic acid along with several known compounds was isolated. Its structure was determined using spectroscopic methods. The cytotoxic activity of zantholic acid against a panel of cancer cell lines was evaluated using the MTT assay. The results show that zantholic acid possesses a selective cytotoxic activity towards breast cancer cell lines.
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