Published January 1, 2013
| Version v1
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Synthesis and Antibacterial and Antifungal Properties of Novel S-, N-, N,S-, and S,O-Substituted 1,4-Naphthoquinone Derivatives
Creators
- 1. Istanbul Univ, Fac Engn, Dept Chem, Istanbul, Turkey
- 2. Beykent Univ, Dept Chem Engn, Fac Engn & Architecture, Istanbul, Turkey
- 3. Istanbul Univ, Dept Elementary Educ, Div Sci Educ, Hasan Ali Yucel Educ Fac, Istanbul, Turkey
- 4. Natl Univ Lviv Polytech, Dept Technol Biol Act Subst Pharm & Biotechnol, Lvov, Ukraine
Description
A novel series of substituted 1,4-naphthoquinone derivatives were synthesized and evaluated for their antibacterial and antifungal activity. The structures of the novel products were characterized by spectroscopic methods. Among the tested compounds, 2,2,3,3-alkoxy substituted naphthoquinones, S,O-substituted naphthoquinone, and N,S-substituted naphthoquinone derivatives are the most potent antifungals against C. tenuis. 2,3-Thio-2,3-alkoxy substituted naphthoquinones are the most effective antifungal compounds against A. niger. Supplemental materials are available for this article. Go to the publisher's online edition ofPhosphorus, Sulfur, and Silicon and the Related Elementsto view the free supplemental file.
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