Published January 1, 2013
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MMP-1, MMP-9, and TIMP-1 levels in oral lichen planus patients with gingivitis or periodontitis
Creators
- 1. Yuzuncu Yil Univ, Fac Dent, Dept Periodontol, TR-65080 Van, Turkey
- 2. Baskent Res Hosp, Dept Dermatol, Konya, Turkey
- 3. Selcuk Univ, Res Ctr, Fac Dent, Konya, Turkey
- 4. Konya Univ, Meram Fac Med, Dept Pathol, Konya, Turkey
- 5. Selcuk Univ, Fac Dent, Dept Periodontol, Konya, Turkey
Description
Objective: Oral lichen planus (OLP) is a chronic inflammatory disease of unknown aetiology. The aim of this study was to investigate matrix metalloproteinase (MMP)-1, MMP-9, and MMP inhibitor-1 (TIMP-1) levels in gingival crevicular fluid (GCF) by enzyme-linked immunosorbent assay and to investigate MMP-1, MMP-9, and TIMP-1 levels in gingival tissue by immunohistochemical staining of samples from patients with and without OLP.
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