Published January 1, 2020 | Version v1
Journal article Open

Anticholinesterase and Antioxidant Activities of Natural Abietane Diterpenoids with Molecular Docking Studies

  • 1. Bezmialem Vakif Univ, Fac Pharm, Dept Pharmacol, TR-34093 Istanbul, Turkey
  • 2. Istanbul Univ, Fac Pharm, Dept Analyt Chem, TR-34116 Istanbul, Turkey
  • 3. Bezmialem Vakif Univ, Fac Pharm, Dept Pharmaceut Biotechnol, TR-34093 Istanbul, Turkey

Description

Background: Alzheimer's Disease (AD) is one of the most prevalent causes of dementia in the world, and no drugs available that can provide a complete cure. Cholinergic neurons of the cerebral cortex of AD patients are lost due to increased activity of cholinesterase enzymes.

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