Published January 1, 2019
| Version v1
Journal article
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Proteomics Analysis of CA1 Region of the Hippocampus in Pre-, Progression and Pathological Stages in a Mouse Model of the Alzheimer's Disease
Creators
- 1. Uludag Univ, Fac Med, Dept Pharmacol, Bursa, Turkey
- 2. Uludag Univ, Fac Med, Dept Physiol, Bursa, Turkey
- 3. Acibadem Mehmet Ali Aydinlar Univ, Fac Med, Dept Pharmacol, Istanbul, Turkey
- 4. Acibadem Labmed R&D Lab, Istanbul, Turkey
- 5. Acibadem Mehmet Ali Aydinlar Univ, Fac Med, Dept Med Biochem, Istanbul, Turkey
Description
Background: CA1 subregion of the hippocampal formation is one of the primarily affected structures in AD, yet not much is known about proteome alterations in the extracellular milieu of this region. Objective: In this study, we aimed to identify the protein expression alterations throughout the pre-pathological, progression and pathological stages of AD mouse model.
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