Published January 1, 2020
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Occupational exposure of dental technicians to methyl methacrylate: Genotoxicity assessment
Creators
- 1. Gulhane Mil Med Acad, Dept Pharmaceut Toxicol, TR-06010 Ankara, Turkey
- 2. Univ Hlth Sci, Dept Pharmaceut Toxicol, Gulhane Fac Pharm, TR-06010 Ankara, Turkey
- 3. Karadeniz Tech Univ, Dept Pharmaceut Toxicol, Fac Pharm, TR-61080 Trabzon, Turkey
- 4. Ankara Univ, Dept Pharmaceut Toxicol, Fac Pharm, TR-06560 Ankara, Turkey
- 5. Gulhane Mil Med Acad, Dept Prosthodont, TR-06010 Ankara, Turkey
Description
Dental technicians may be chronically exposed to methyl methacrylate (MMA), used in the production of dental prostheses. We have studied whether occupational exposure to MMA affects genotoxicity biomarkers such as 8-OHdG formation, comet assay, and buccal micronucleus frequency. MMA exposure was assessed via ambient air analysis. Although no significant differences between exposed and non-exposed individuals were seen with respect to blood genotoxicity measurements, we found a higher level of buccal-cell anomalies in the exposed group.
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