Published January 1, 2020
| Version v1
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The anxiolytic effect of perampanel and possible mechanisms mediating its anxiolytic effect in mice
Creators
- 1. Anadolu Univ, Fac Pharm, Dept Pharmacol, TR-26470 Eskisehir, Turkey
Description
Aims: The aim of this study is to investigate the anxiolytic activity of perampanel, a non-competitive antagonist of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-type glutamate receptors, which is approved for partial-onset seizures in patients with epilepsy, and its mechanism of action.
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