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Published January 1, 2015 | Version v1
Journal article Open

TDS exposure project: Application of the analytic hierarchy process for the prioritization of substances to be analyzed in a total diet study

Creators

  • 1. Agence Natl Securite Sanitaire Alimentat Environm, ANSES, French Agcy Food Environm & Occupat Hlth Safety, F-94701 Maisons Alfort, France
  • 2. Univ Ghent, Dept Publ Hlth, B-9000 Ghent, Belgium
  • 3. Natl Inst Hlth, Ist Super Sanita, Dept Food Safety & Vet Publ Hlth, I-00161 Rome, Italy
  • 4. TUBITAK Marmara Res Ctr, Food Inst, TR-41470 Kocaeli, Turkey
  • 5. Ctr Ric Alimenti NUTriz CRA NUT, Consiglio Ric Sperimentaz Agri CRA, I-00178 Rome, Italy
  • 6. Agencia Espanola Seguridad Alimentaria & Nutr, Madrid 28071, Spain
  • 7. Croatian Food Agcy, Hrvatska Agencija Hranu, Osijek 31000, Hrvatska, Croatia

Description

The objective of this article is to develop a general method based on the analytic hierarchy process (AHP) methodology to rank the substances to be studied in a Total Diet Studies (TDS). This method was tested for different substances and groups of substances (N = 113), for which the TDS approach has been considered relevant. This work was performed by a group of 7 experts from different European countries representing their institutes, which are involved in the TDS EXPOSURE project. The AHP methodology is based on a score system taking into account experts' judgments quantified assigning comparative scores to the different identified issues. Hence, the 10 substances of highest interest in the framework of a TDS are trace elements (methylmercury, cadmium, inorganic arsenic, lead, aluminum, inorganic mercury), dioxins, furans and polychlorinated biphenyls (PCBs), and some additives (sulfites and nitrites). The priority list depends on both the national situation (geographical variations, consumer concern, etc.) and the availability of data. Thus, the list depends on the objectives of the TDS and on reachable analytical performances. Moreover, such a list is highly variable with time and new data (e.g. social context, vulnerable population groups, emerging substances, new toxicological data or health-based guidance values). (C) 2014 Elsevier Ltd. All rights reserved.

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