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Functional deficits and morphological changes in the neurogenic bladder match the severity of spinal cord compression

2012    Ozsoy, O.; Ozsoy, U.; Stein, G.; Semler, O.; Skouras, E.; Schempf, G.; Wellmann, K.; Wirth, F.; Angelova, S.; Ankerne, J.; Ashrafi, M.; Schoenau, E.; Papamitsou-Sidoropolou, T.; Jaminet, P.; Sarikcioglu, L.; Irintchev, A.; Dunlop, S. A.; Angelov, D. N.

Following spinal cord injury (SCI), loss of spinal and supraspinal control results in desynchronisation of detrusor vesicae (parasympathicus) and external urethral sphincter (sympathicus) activity. Despite recovery of lower urinary tract function being a high priority in patients with SCI, effective treatment options are unavailable largely because mechanisms are poorly understood.