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Resveratrol Stimulates Hydrogen Sulfide (H2S) Formation to Relax Murine Corpus Cavernosum

   Yetik-Anacak, Gunay; Dereli, Mehmet V.; Sevin, Gulnur; Ozzayim, Ozge; Erac, Yasemin; Ahmed, Asif

IntroductionResveratrol (RVT) found in red wine protects against erectile dysfunction and relaxes penile tissue (corpus cavernosum) via a nitric oxide (NO) independent pathway. However, the mechanism remains to be elucidated. Hydrogen sulfide (H2S) is a potent vasodilator and neuromodulator generated in corpus cavernosum.

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