Published January 1, 2015 | Version v1
Journal article Open

Integromic Analysis of Genetic Variation and Gene Expression Identifies Networks for Cardiovascular Disease Phenotypes

  • 1. Middle E Tech Univ, Dept Chem Engn, TR-06531 Ankara, Turkey
  • 2. Bilkent Univ, Dept Comp Engn, Ankara, Turkey
  • 3. Harvard Univ, Sch Med, Boston, MA USA
  • 4. Univ Massachusetts, Sch Med, Dept Med, Worcester, MA USA
  • 5. NIH, Math & Stat Comp Lab, Ctr Informat Technol, Bethesda, MD 20892 USA

Description

Background-Cardiovascular disease (CVD) reflects a highly coordinated complex of traits. Although genome-wide association studies have reported numerous single nucleotide polymorphisms (SNPs) to be associated with CVD, the role of most of these variants in disease processes remains unknown.

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