Yayınlanmış 1 Ocak 2020
| Sürüm v1
Dergi makalesi
Açık
Azacyanines as Novel Topoisomerase II Alpha Inhibitors
Oluşturanlar
- 1. Middle East Tech Univ, Biochem Program, TR-06800 Ankara, Turkey
- 2. Middle East Tech Univ, Dept Chem, TR-06800 Ankara, Turkey
Açıklama
Introduction: Topoisomerase II alpha (Topo II alpha) has become one of the extensively exploited targets in chemotherapy due to its role in regulating the topological constraints of DNA during replication and transcription. Small molecules targeting Topo II alpha's activity such as etoposide (VP-16) and doxorubicin are extensively used in the treatment of many different types of cancer.
Dosyalar
bib-5fc8334a-23aa-43a7-93df-eadfde2ff274.txt
Dosyalar
(181 Bytes)
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md5:cc97b910c9d0040df86968a1b42fb032
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181 Bytes | Ön İzleme İndir |