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Synthesis and in vitro study of new highly boronated phthalocyanine

   Shmal'ko, Akim V.; Efremenko, Anastasija V.; Ignatova, Anastasija A.; Sivaev, Igor B.; Feofanov, Alexey V.; Hamuryudan, Esin; Guel, Ahmet; Kovalenko, Leonid V.; Qi, Shicheng; Bregadze, Vladimir I.

A new highly boronated Zn(II)-phthalocyanine with eight cobalt bis(dicarbollide) units (144 boron atoms) was prepared and its intracellular accumulation and distribution in GL6 human glioblastoma cells were studied. It was found that the boronated phthalocyanine undergoes strong aggregation in intracellular environment.

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