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Multi-Wavelength Photo-Magnetic Imaging System for Photothermal Therapy Guidance

2020    Algarawi, Maha; Erkol, Hakan; Luk, Alex; Ha, Seunghoon; Burcin Unlu, Mehmet; Gulsen, Gultekin; Nouizi, Farouk

Background and Objectives In photothermal therapy, cancerous tissue is treated by the heat generated from absorbed light energy. For effective photothermal therapy, the parameters affecting the induced temperature should be determined before the treatment by modeling the increase in temperature via numerical simulations. However, accurate simulations can only be achieved when utilizing the accurate optical, thermal, and physiological properties of the treated tissue. Here, we propose a multi-wavelength photo-magnetic imaging (PMI) technique that provides quantitative and spatially resolved tissue optical absorption maps at any wavelength within the near-infrared (NIR) window to assist accurate photothermal therapy planning.