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A facile palladium catalysed 3-component cascade route to functionalised isoquinolinones and isoquinolines

2016    Grigg, Ronald; Elboray, Elghareeb E.; Akkarasamiyo, Sunisa; Chuanopparat, Nutthawat; Dondas, H. Ali; Abbas-Temirek, Hussien H.; Fishwick, Colin W. G.; Aly, Moustafa F.; Kongkathip, Boonsong; Kongkathip, Ngampong

Palladium catalysed three component cascade process, involving coupling of 2-iodobenzoates, -benzaldehydes, or acetophenones with substituted allenes and ammonium tartrate as an ammonium surrogate, provides a novel and facile route to substituted functionalised isoquinolinones and isoquinolines in good yields.