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Microarray Analysis of the Genes Associated With Osteitis in Chronic Rhinosinusitis

   Gunel, Ceren; Bleier, Benjamin S.; Bozkurt, Gokay; Eliyatkin, Nuket

Objectives/Hypothesis: Although numerous studies have examined epithelial remodeling in chronic rhinosinusitis (CRS), bone remodeling (osteitis) has only recently gained attention as a potential significant contributor to the pathophysiology of recalcitrant CRS. The purpose of this study was to compare gene expression profiles between osteitic bone and the adjacent diseased mucosa in patients with CRS to determine which genes affect mucosal and bony remodeling.

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