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Triterpene saponins from the roots of Acacia albida Del. (Mimosaceae)

2017    Tchoukoua, Abdou; Tabopda, Turibio Kuiate; Uesugi, Shota; Ohno, Misa; Kimura, Ken-ichi; Kwon, Eunsang; Momma, Hiroyuki; Horo, Ibrahim; Caliskan, Ozgen Alankus; Shiono, Yoshihito; Ngadjui, Bonaventure Tchaleu

Seven previously undescribed bidesmosidic triterpenoid saponins named albidosides A - G, were isolated from a methanol extract of the roots of Acacia albida. Their structures were elucidated using 1D and 2D NMR spectroscopy and mass spectrometry and determined to be bidesmosides of oleanolic acid and of 16 alpha-hydroxyoleanolic acid. Albidosides B - G were assayed for their cytotoxicity against HeLa and HL60 cells using MTT method and microscopic observation. (C) 2016 Elsevier Ltd. All rights reserved.