Dergi makalesi Açık Erişim

Genotypes of hepatitis a virus in Turkey: first report and clinical profile of children infected with sub-genotypes IA and IIIA

2017    Yilmaz, Huseyin; Karakullukcu, Asiye; Turan, Nuri; Cizmecigil, Utku Y.; Yilmaz, Aysun; Ozkul, Ayse A.; Aydin, Ozge; Gunduz, Alper; Mete, Mahmut; Zeyrek, Fadile Y.; Kirazoglu, Taner T.; Richt, Juergen A.; Kocazeybek, Bekir

Background: Hepatitis A virus (HAV) is a food and water-borne virus causing clinical (mainly hepatitis) and subclinical disease in humans. It is important to characterize circulating strains of HAV in order to prevent HAV infections using efficacious vaccines. The aim of this study was the detection and characterization of the circulating strains of HAV in Turkey by performing serology, RT-PCR, sequencing and phylogenetic analysis.