Dergi makalesi Açık Erişim

Impact of Neuro-Behcet Disease Immunoglobulin G on Neuronal Apoptosis

2017    Giris, Murat; Bireller, Sinem; Kucukali, Cem Ismail; Hanagasi, Hasmet; Degirmencioglu, Sevgin; Tuzun, Erdem

Introduction: Parenchymal neuro-Behcet disease (NBD) is encountered in 5%-15% of Behcet disease (BD) patients and is characterized by inflammation of the brainstem and diencephalon structures. Neuronal apoptosis has been shown to participate in neuronal cell loss. Anti-neuronal antibodies have been identified in NBD patients. However, the pathogenic properties of these antibodies have not been studied.