Dergi makalesi Açık Erişim

Discovery of new Toxoplasma gondii antigenic proteins using a high throughput protein microarray approach screening sera of murine model infected orally with oocysts and tissue cysts

2018    Doskaya, Mert; Liang, Li; Jain, Aarti; Can, Huseyin; Iz, Sultan Gulce; Felgner, Philip Louis; Doskaya, Aysu Degirmenci; Davies, David Huw; Guruz, Adnan Yuksel

Background: Toxoplasma gondii is an obligate intracellular protozoan parasite that causes congenital toxoplasmosis, as well as other serious clinical presentations in immune compromised humans. The parasite has also been recently linked to behavioral diseases in humans and other mammalian hosts. New antigens are being evaluated to develop a diagnostic kit for the diagnosis of acute infection or a protective vaccine.