Dergi makalesi Açık Erişim

Therapeutic potential of conditioned medium obtained from deferoxamine preconditioned umbilical cord mesenchymal stem cells on diabetic nephropathy model

2022    Ozkan, Serbay; Isildar, Basak; Ercin, Merve; Gezginci-Oktayoglu, Selda; Konukoglu, Dildar; Nesetoglu, Neset; Oncul, Mahmut; Koyuturk, Meral

Background: The therapeutic potential of mesenchymal stem cells (MSCs)-derived conditioned media (CM) can be increased after preconditioning with various chemical agents. The aim of this study is comparative evaluation of effects of N-CM and DFS-CM which are collected from normal (N) and deferoxamine (DFS) preconditioned umbilical cord-derived MSCs on rat diabetic nephropathy (DN) model.