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A comparison of miRNAs with proinflammatory cytokines and procalcitonin of sepsis in the intensive care unit A comparison of miRNAs with proinflammatory cytokines and procalcitonin

2022    Orhan, Semiha; Gulsoy, Kemal Yetis; Yaylagul, Esra Orenlili; Koca, Halit Bugra; Yavuz, Lutfi; Ulger, Celal

Aim: The development of sepsis, the low efficacy of antibiotics used, long-term antibiotic use, and the development of resistance to antibiotics are significant problems in patients in intensive care units. The use of biological markers is promising for the diagnosis and treatment of sepsis. In this study, proinflammatory cytokines, procalcitonin and four miRNA expressions were analyzed in a time-dependent manner in a patient group and control group, and the correlations between them were examined.