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CYTOTOXIC AND ANTIBACTERIAL SESQUITERPENES FROM INULA-GRAVEOLENS

1993    TOPCU, G; OKSUZ, S; SHIEH, HL; CORDELL, GA; PEZZUTO, JM; BOZOKJOHANSSON, C

A further study on the aerial parts of Inula graveolens afforded a new eudesmanolide, 11,13-dihydroivalin and four known sesquiterpene lactones, ivalin, inuviscolide, 8-epi-inuviscolide, 8-epi-xanthatin-1beta,5beta-epoxide, in addition to the previously isolated compounds. The structures were established by spectral methods and the compounds were evaluated for their cytotoxic and antibacterial activity.