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SESQUITERPENE LACTONES FROM TANACETUM-ARGENTEUM

   GOREN, N; TAHTASAKAI, E; PEZZUTO, JM; CORDELL, GA; SCHWARZ, B; PROKSCH, P

The flowers of Tanacetum argenteum subsp. argenteum yielded two new germacranolides, in addition to some known sesquiterpene lactones. The structures were elucidated by spectral methods and chemical transformations. 8 alpha-Angeloyloxycostunolide showed cytotoxic activity and antifeedant activity against neonate larvae of Spodoptera littoralis.

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