A new biflavonoid from Solanum dulcamara L. and investigation of anti-hyperglycaemic activity of its fruit extract

A new biflavone, 6,2 ',3 '',5 '',4"'-pentahydroxy-3,7 ''-biflavone, has been isolated from the fruits of Solanum dulcamara L., in addition to two known compounds, beta-sitosterol and stigmasterol. Their structures were established on the basis of UV, IR, 1D, 2D NMR and HR-ESI-MS spectroscopic methods. The anti-hyperglycaemic effect of S. dulcamara was investigated using diabetic rats. The anti-hyperglycaemic activity of the fruit extract of S. dulcamara was presented for the first time in this study.