Published January 1, 2015 | Version v1
Journal article Open

Clinical characteristics and molecular genetic analysis of 22 patients with neonatal diabetes from the South-Eastern region of Turkey: predominance of non-K-ATP channel mutations

  • 1. Children State Hosp, Dept Paediat Endocrinol, TR-21100 Diyarbakir, Turkey
  • 2. Univ Exeter, Sch Med, Inst Biomed & Clin Sci, Exeter EX2 5DW, Devon, England
  • 3. Children State Hosp, Dept Neonatol, TR-21100 Diyarbakir, Turkey
  • 4. Dicle Univ, Dept Med Biol & Genet, TR-21100 Diyarbakir, Turkey
  • 5. Univ Southampton, Fac Med, Southampton SO16 6YD, Hants, England

Description

Background: Neonatal diabetes mellitus (NDM) is a rare form of monogenic diabetes and usually presents in the first 6 months of life. We aimed to describe the clinical characteristics and molecular genetics of a large Turkish cohort of NDM patients from a single centre and estimate an annual incidence rate of NDM in South-Eastern Anatolian region of Turkey.

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