Published January 1, 2015
| Version v1
Journal article
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Near-infrared spectroscopy-intravascular ultrasound: scientific basis and clinical applications
Creators
- 1. Royal Brompton Hosp, NIHR Cardiovasc BRU, London SW3 6NP, England
- 2. Infraredx Inc, Burlington, MA USA
- 3. Mt Sinai Hosp, New York, NY 10029 USA
- 4. Beaumont Hosp, Dept Cardiovasc Med, Royal Oak, MI USA
Description
Coronary angiography underestimates the magnitude of the atherosclerotic burden and cannot detect the presence of disease in the early phases. Recognition of these inherent limitations of angiography has been an impetus for the development of other coronary imaging techniques. The novel near-infrared spectroscopy-intravascular ultrasound (NIRS-IVUS) catheters can detect and quantify the presence of lipid core in the atherosclerotic plaque and associate it with other features such as lumen size and plaque architecture. Lipid-rich plaques are known to pose a higher risk of distal embolization during interventions and plaque disruption. The aim of this manuscript is the review of the potential clinical and research applications of this technology as highlighted by recent studies.
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