Published January 1, 2016 | Version v1
Journal article Open

Clinical significance of ADAMTS1, ADAMTS5, ADAMTS9 aggrecanases and IL-17A, IL-23, IL-33 cytokines in polycystic ovary syndrome

  • 1. Diskapi Yildirim Beyazit Training & Res Hosp, Dept Endocrinol & Metab, Irfan Bastug Caddesi, TR-06110 Ankara, Turkey
  • 2. Turgut Ozal Univ, Dept Med Biol, Sch Med, Ankara, Turkey
  • 3. Ankara Univ, Sch Med, Dept Endocrinol & Metab, Ankara, Turkey
  • 4. Turgut Ozal Univ, Dept Biochem, Sch Med, Ankara, Turkey
  • 5. Hacettepe Univ, Dept Biostat, Fac Med, Ankara, Turkey

Description

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women of reproductive age. A disintegrin and metalloproteinase with thrombospondin-like motifs (ADAMTS) are involved in inflammation and fertility. The aim of this investigation was to evaluate the serum levels of ADAMTS1, ADAMTS5, ADAMTS9, IL-17, IL-23, IL-33 and to find out the relationship between these inflammatory cytokines and ADAMTSs in PCOS patients.

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