Published January 1, 2016
| Version v1
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Subarachnoid transplantation of autologous neurogenically induced bone marrow derived mesenchymal stem cells for the treatment of fibrocartilaginous embolic myelopathy in two dogs
Creators
- 1. Ankara Univ, Fac Vet Med, Dept Surg, TR-06100 Ankara, Turkey
Description
The objective of this study was to investigate the effects of autologous neurogenically induced bone marrow-derived mesenchymal stem cells (NIBM-MSCs) in two dogs suspected to have fibrocartilaginous embolic myelopathy FCEM). Both dogs were paraplegic without deep pain perception DPP) and tentatively diagnosed by MRI. Autologous NIBM-MSCs (5 x 10(6)) were transplanted into the lumbar subarachnoid space two times with a 21-day interval for each patient. Based on a 21-month follow-up of the treated animals, the transplantation of NIBM-MSCs seems to be promising in subjects with FCEM lacking DPP.
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